What’s the go with verteporfin? 12/6/2023
The conversation discusses using verteporfin for hair regrowth and minimizing scarring after hair transplants. Some individuals plan to self-administer verteporfin, potentially in combination with microneedling, as an alternative to hair transplants.
View this post in the Community →
Similar Community Posts Join
5 / 5 resultscommunity What do you think will be the next "big innovation" regarding AGA?
The conversation discusses potential new treatments for androgenetic alopecia (AGA), including verteporfin, pyrilutamide, and hair cloning. There is optimism about scientific advancements providing alternatives to minoxidil and finasteride.
community What happened with verteporfin?
Verteporfin, combined with microneedling, shows promise for hair regrowth by allowing hair follicles to grow in wounds, but it's expensive and painful. Pai-1 inhibitors may also help prevent hair loss by degrading fibrosis, and some users continue using minoxidil alongside these treatments.
community What do you think about this? he says one of the causes of pattern hair loss is scars and it can be fixed
The conversation discusses hair loss treatments, focusing on insulin resistance, microneedling with topical melatonin, and stress reduction. Users express skepticism about the advice, preferring proven treatments like minoxidil and finasteride, while some mention alternative methods like dermal incisions and verteporfin for reducing fibrosis.
community What are your unpopular opinions on hair loss and its treatments?
Hair loss treatments like finasteride, minoxidil, and hair transplants are more accessible and effective now. Concerns about side effects and skepticism about new treatments like hair cloning and GT20029 remain.
community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year
A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
Related Research
6 / 6 results
research Controlled microtrauma opens a regenerative window for appendage-bearing skin repair
This study tested a microneedle patch on rabbit and pig models to support skin regeneration, revealing that the treatment accelerated wound closure, reduced scar formation, and promoted hair-bearing tissue and follicle growth, suggesting a trauma-guided framework for skin restoration.
research Microneedles as transdermal drug delivery system for enhancing skin disease treatment
This review explores how microneedles can improve the delivery of dermatological treatments by bypassing the skin's outer barrier, discussing their potential use in managing skin diseases, cosmetic applications, and challenges related to clinical adoption.
research Microneedle-Mediated Transdermal Drug Delivery for the Treatment of Multiple Skin Diseases
This study highlights the clinical potential of microneedles as an innovative transdermal drug delivery system for treating various skin diseases with minimal pain and high patient compliance.
research Use of Verteporfin with Dermal Wounding to Regenerate New Hair in Androgenetic Alopecia
In this study, two male patients with androgenetic alopecia who had previously undergone hair transplants showed increased hair regrowth after receiving verteporfin injections, with a 63% mean increase in dense donor sites, 38% in thinning areas, but no growth in bald areas.
research Use of Verteporfin to Regrow Hair and Reduce Fibrosis after Transplantation
In this Stanford study, verteporfin was used to promote scarless skin regeneration by inhibiting YAP activity in a 27-year-old female, resulting in increased hair density at the treated site compared to the untreated control.
research Inhibition of the Hippo pathway by verteporfin reduces the proliferation and stemness of rat hair follicle neural crest stem cells under hypoxia
In this study, hypoxic conditions were found to enhance stemness in hair follicle neural crest stem cells, while inhibiting the Hippo pathway significantly decreased their proliferation.