Use of Verteporfin to Regrow Hair and Reduce Fibrosis After Transplantation

    Melissa Toyos, Rolando Toyos, Allison Toyos
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    Studysummary In this Stanford study, verteporfin was used to promote scarless skin regeneration by inhibiting YAP activity in a 27-year-old female, resulting in increased hair density at the treated site compared to the untreated control. Our plain-language summary of this paper — not a Tressless recommendation.
    The study explores the use of verteporfin, an FDA-approved drug for wet macular degeneration, to promote hair regrowth and reduce fibrosis after hair transplantation. A 27-year-old female underwent a hair transplant with 1,000 grafts, receiving verteporfin treatment on one side of the incision. After 8 weeks, the treated side showed increased hair density (20x21 mm) compared to the control side (12x16 mm), with similar hair texture. The findings suggest verteporfin's potential in enhancing cosmetic and functional recovery post-transplant, warranting further research.
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