Platelet-Rich Plasma Injection and Lipofilling-Assisted Hair Transplantation on Residual Scalp Alopecia Post Aplasia Cutis Congenita Verticis

This study reports on a 16-year-old female with residual scalp alopecia from aplasia cutis congenita verticis (ACCV), treated using follicular unit transplantation (FUT), platelet-rich plasma (PRP) injections, and fat grafting. The combination therapy aimed to enhance hair follicle engraftment and improve skin quality in the scarred area. Over a 4-year follow-up, the patient experienced significant improvements in hair density and follicle survival rates, with 70% after the first transplant and 80% after the second. Additionally, skin characteristics such as thickness, vascularization, and sensitivity improved. The study suggests that combining regenerative techniques like PRP and fat grafting with FUT may be effective for treating cicatricial alopecia, indicating the need for further research.