Up-To-Date Clinical Trials of Hair Regeneration Using Conditioned Media of Adipose-Derived Stem Cells in Male and Female Pattern Hair Loss

The document from 2017 discussed the potential of adipose-derived stem cells (ADSCs) as a therapeutic option for hair loss. The primary roles of mesenchymal stem cells (MSCs), which ADSCs are a source of, are to maintain the stem cell niche, facilitate recovery after injury, and ensure healthy aging and the homeostasis of organs and tissues. ADSCs can replace degenerated cells in affected organs and exhibit beneficial effects through the paracrine actions of various cytokines and growth factors. Laboratory experiments and animal studies have shown that ADSC-related proteins can stimulate hair growth. The authors also conducted clinical pilot studies using conditioned media of ADSCs for pattern hair loss in men and women, concluding that this approach represents a promising alternative therapeutic strategy for hair loss.