Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling

    September 2011 in “ Cell ”
    Eric Festa, Jackie A. Fretz, Ryan Berry … Valerie Horsley
    Studysummary This study found that intradermal adipocyte lineage cells in mice are necessary and sufficient to activate follicular stem cells, highlighting their role in regulating skin stem cell activity.
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    Research cited in this study 8

    1. Stem Cells and the Niche: A Dynamic Duo Cell Stem Cell · 2010
    2. Hair Growth Stimulated by Conditioned Medium of Adipose-Derived Stem Cells Is Enhanced by Hypoxia: Evidence of Increased Growth Factor Secretion Biomedical research · 2010
    3. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009
    4. Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008
    5. PDGF Isoforms Induce and Maintain Anagen Phase of Murine Hair Follicles Journal of Dermatological Science · 2006
    6. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005
    7. Asebia-2J (Scd1ab2J): A New Allele and a Model for Scarring Alopecia ˜The œAmerican journal of pathology · 2000
    8. Obesity and Female Androgenic Alopecia: A Cause and an Effect? Journal of The American Academy of Dermatology · 1994