The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine

    Mehrdad T. Kiani, Claire A. Higgins, Benjamin D. Almquist
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    TLDR Hair follicles are valuable for regenerative medicine and wound healing.
    The hair follicle was highlighted as a valuable source for regenerative medicine due to its unique ability to selectively degenerate and regenerate. It influenced wound healing, angiogenesis, and neurogenesis, and contained distinct stem cell populations, which were used in clinical trials for tendinosis and chronic ulcers. Additionally, keratin from hair fibers provided abundant biomaterials for regenerative applications. The review covered the hair follicle's structure, its role in skin microenvironment regulation, the impact on wound healing, and the potential of keratin-based biomaterials.
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