Destruction of the Arrector Pili Muscle and Fat Infiltration in Androgenic Alopecia

    March 2014 in “ British Journal of Dermatology ”
    Niloufar Torkamani, Nicholas W Rufaut, L. Jones, Robert Sinclair
    Studysummary This study found that in androgenic alopecia, the arrector pili muscle degenerates and is replaced by fat, unlike in normal skin or telogen effluvium.
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    Research cited in this study 17

    1. Dermal Papilla Cell Number Specifies Hair Size, Shape, and Cycling, and Its Reduction Causes Follicular Decline Development · 2013
    2. Clinical and Histological Challenge in the Differential Diagnosis of Diffuse Alopecia: Female Androgenetic Alopecia, Telogen Effluvium and Alopecia Areata – Part I Anais Brasileiros De Dermatologia · 2012
    3. Miniaturized Hairs Maintain Contact With the Arrector Pili Muscle in Alopecia Areata but Not in Androgenetic Alopecia: A Model for Reversible Miniaturization and Potential for Hair Regrowth International Journal of Trichology · 2012
    4. Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia PLOS ONE · 2012
    5. De Novo Production of Dermal Papilla Cells During the Anagen Phase of the Hair Cycle Journal of Investigative Dermatology · 2010
    6. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    7. Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells Dermatology · 2007
    8. Cultured Cells From the Adult Human Hair Follicle Dermis Can Be Directed Toward Adipogenic and Osteogenic Differentiation Journal of Investigative Dermatology · 2005
    9. Dermal Papilla-Induced Hair Differentiation of Adult Epithelial Stem Cells from Human Skin Physiological Genomics · 2004
    10. The Reliability of Horizontally Sectioned Scalp Biopsies in the Diagnosis of Chronic Diffuse Telogen Hair Loss in Women Journal of The American Academy of Dermatology · 2004
    11. Hair Follicle Dermal Cells Differentiate Into Adipogenic and Osteogenic Lineages Experimental Dermatology · 2003
    12. Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme: Implications for Hair Growth Control Journal of Investigative Dermatology · 2003
    13. Computerized Morphometry and Three-Dimensional Image Reconstruction in the Evaluation of Scalp Biopsy from Patients with Non-Cicatricial Alopecias British Journal of Dermatology · 2003
    14. The Arrector Pili Muscle and the Follicular Unit of the Scalp: A Microscopic Anatomy Study Dermatologic Surgery · 2002
    15. Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss Journal of The American Academy of Dermatology · 2001
    16. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    17. Male Pattern Alopecia: A Histopathologic and Histochemical Study Journal of Cutaneous Pathology · 1975

    Related research 6

    1. Feature Characterization of Scarring and Non-Scarring Types of Alopecia by Multiphoton Microscopy 2018
    2. Psoriatic Alopecia Clinical and Experimental Dermatology · 2015
    3. Destruction of the Arrector Pili Muscle and Fat Infiltration in Androgenic Alopecia British Journal of Dermatology · 2014
    4. The Arrector Pili Muscle and the Follicular Unit of the Scalp: A Microscopic Anatomy Study Dermatologic Surgery · 2002
    5. Hot Comb Alopecia Archives of Dermatology · 1968
    6. Hot Comb Alopecia PubMed · 1968