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GlossaryArrector Pili Muscle

small muscle causing hair to stand up, creating goosebumps

The arrector pili muscle is a small, smooth muscle attached to the base of a hair follicle. When it contracts, usually in response to cold or emotional stimuli, it causes the hair to stand up, a phenomenon known as "goosebumps." This muscle plays a role in thermoregulation and can also be involved in the body's response to stress.

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The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit

research The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit

47 citations, September 2008 in “British Journal of Dermatology”

Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.

research Styling Without Shedding: Novel Topical Formula Reduces Hair Shedding by Contracting the Arrector Pili Muscle

November 2017 in “Dermatologic Therapy”

A new topical solution safely reduces hair shedding by 38% on average by tightening a muscle in the scalp.

research Scalp Neuropathy in Androgenetic Alopecia

1 citations, January 2021 in “Journal of The American Academy of Dermatology”

Scalp nerve issues are linked to hair loss in men.

research Phenobarbital

January 2014 in “Reactions Weekly”

A woman experienced unusual hair loss and skin reactions after taking phenobarbital, but her hair grew back after treatment.

research Breakthroughs in the Diagnosis and Treatment of Male and Female Pattern Hair Loss

January 2016 in “Journal of clinical & experimental dermatology research”

New methods can diagnose hair loss by examining the scalp and can treat it with a mix of oral and topical medications, along with cosmetic procedures like hair transplants.

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Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 2 months ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community Do hair follicles dies or are dormant ?

in Finasteride/Dutasteride 92 upvotes 3 months ago

Hair follicles can be dormant and potentially revived with treatments like finasteride and minoxidil, but irreversible loss occurs if certain structures are destroyed. Early intervention is more effective, and additional methods like microneedling may help.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

in Research/Science 2 upvotes 2 months ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community Confused why people are calling PP405 a cure...it never claimed to be able to undo miniaturization or revert vellus back to terminal hairs. It seems to be more of a growth stimulant like minoxidil.

in Research/Science 54 upvotes 1 month ago

PP405 is not a cure for hair loss but may reactivate dormant hair follicles, similar to minoxidil. It is unlikely to help with miniaturized or vellus hairs and is still in trial phases, with availability expected around 2030.

community HRT is literal black magic. Fin 1 mg/day @ 4 years, min 2x/day @ 3 years, Estradiol 4mg/day @ 3.5 months, and Spironolactone 100mg/day @ 3.5 months (estra & spiro are medicines you should likely not take if you are a cis man)

in Progress Pictures 118 upvotes 6 months ago

User shared progress on hair regrowth using Fin 1 mg/day for 4 years, Min 2x/day for 3 years, Estradiol 4mg/day, and Spironolactone 100mg/day for 3.5 months. They noted significant hairline recovery and advised against HRT for cis men due to feminizing effects.

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