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GlossaryArrector Pili Muscle

small muscle causing hair to stand up, creating goosebumps

The arrector pili muscle is a small, smooth muscle attached to the base of a hair follicle. When it contracts, usually in response to cold or emotional stimuli, it causes the hair to stand up, a phenomenon known as "goosebumps." This muscle plays a role in thermoregulation and can also be involved in the body's response to stress.

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Adipose Infiltration of the Dermis, Involving the Arrector Pili Muscle, and Dermal Displacement of Eccrine Sweat Coils: New Histologic Observations in Frontal Fibrosing Alopecia

research Adipose Infiltration of the Dermis, Involving the Arrector Pili Muscle, and Dermal Displacement of Eccrine Sweat Coils: New Histologic Observations in Frontal Fibrosing Alopecia

6 citations , January 2019 in “The American Journal of Dermatopathology”

The conclusion is that fat tissue in the skin is a new finding in Frontal fibrosing alopecia and may contribute to hair follicle and muscle degeneration.

research Novel Shampoo Reduces Hair Shedding by Contracting the Arrector Pili Muscle via the Trace Amine-Associated Receptor

3 citations , July 2019 in “Journal of Cosmetic Dermatology”

New shampoo with tyramine hydrochloride reduces hair loss by making a small muscle in the hair follicle contract.

Faculty Opinions Recommendation of Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches

research Faculty Opinions Recommendation of Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches

September 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Scientists successfully created fully functional hair follicles using bioengineering methods and stem cells.

research The Arrector Pili Muscle: The Bridge Between the Follicular Stem Cell Niche and the Interfollicular Epidermis

14 citations , July 2016 in “Anatomical Science International”

The study suggests that the arrector pili muscle is important for hair health and its damage might contribute to hair loss.

Beyond Goosebumps: Interactions Between the Hair Follicle, the Arrector Pili Muscle, and the Sympathetic Nerve During Development and Hair Follicle Regeneration

research Beyond Goosebumps: Interactions Between the Hair Follicle, the Arrector Pili Muscle, and the Sympathetic Nerve During Development and Hair Follicle Regeneration

April 2018 in “Journal of Investigative Dermatology”

Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.

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community My slick bald temples ( for about 7-8 years ) FIN MIN KETO MICRONEEDLING 2 months +

in Progress Pictures 54 upvotes 3 years ago

A user sharing their progress after using Fin, Minoxidil, keto diet, and microneedling for two months to attempt to regrow hair on bald temples. Other users replied with advice and support.

community HRT is literal black magic. Fin 1 mg/day @ 4 years, min 2x/day @ 3 years, Estradiol 4mg/day @ 3.5 months, and Spironolactone 100mg/day @ 3.5 months (estra & spiro are medicines you should likely not take if you are a cis man)

in Progress Pictures 118 upvotes 1 year ago

User shared progress on hair regrowth using Fin 1 mg/day for 4 years, Min 2x/day for 3 years, Estradiol 4mg/day, and Spironolactone 100mg/day for 3.5 months. They noted significant hairline recovery and advised against HRT for cis men due to feminizing effects.

community progress has been insane, been having a bad shed for about a month or 2, can anyone explain?

in Progress Pictures 678 upvotes 1 year ago

User experienced significant hair regrowth using minoxidil and dutasteride, along with microneedling, vitamins, and massages. Despite recent shedding, they hope it's a synchronized hair cycle and plan to continue the treatment.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 2 years ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community 22 yr asian male 2 year fin results

in Progress Pictures 135 upvotes 2 years ago

The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

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