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      community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

       23 upvotes 1 year ago
      Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

      community The Battle of Norwood (2024) | Dut 0.5 mg ED + Oral Min 5 mg ED

      in Progress Pictures  518 upvotes 1 year ago
      The conversation discusses hair regrowth using dutasteride and oral minoxidil, with the user reporting significant improvement in hair volume after combining these treatments. Some side effects mentioned include changes in libido and increased facial hair, but overall, the user is satisfied with the results.

      community Exercising completely negated my finasteride sides.

       5 upvotes 6 years ago
      Exercise improved minor side effects of finasteride, such as reduced ejaculatory volume and depression, and also helped with gyno. Running and push-ups were particularly effective, leading to increased ejaculatory volume and improved mental clarity.

      community first comment under every progress post

       1406 upvotes 4 months ago
      Hair loss treatments like finasteride and dutasteride are discussed, with users sharing experiences of side effects such as changes in libido and ejaculate volume. Despite these side effects, many find the treatments worthwhile for maintaining hair.