Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better? Finasteride/Dutasteride 1/13/2025
Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.
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