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research Mitoxantrone
Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

research Effect of Finasteride Particle Size Reduction on Its Pharmacokinetic, Tissue Distribution, and Cellular Permeation
Smaller finasteride particles increase effectiveness in treating hair loss.

research Studies on the Disposition of Finasteride: Absorption, Distribution, and Excretion of (14C)finasteride After Single Oral or Intravenous Administration in Rats
Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.

research Recent Studies on the Delivery of Hydrophilic Drugs in Nanoparticulate Systems
Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

research The Role of Dutasteride in the Treatment of Benign Prostatic Obstruction and Related Conditions
Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.
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5 / 603 resultscommunity Why don't people start with low-dose of dutasteride?
The conversation discusses the use of dutasteride and finasteride for hair loss, with a focus on starting with low doses of dutasteride to match the DHT suppression of finasteride. It highlights the longer half-life and potential side effects of dutasteride, as well as the preference for finasteride due to its availability and research backing.
community Dutasteride isn’t working confirmed by test.
Dutasteride isn't effectively reducing DHT levels, prompting a switch back to finasteride. The user questions the reliability of their DHT test results due to hair loss concerns.
community Fin/Dut and Metabolism Speeds…
A user speculates that a fast metabolism might affect the effectiveness of dutasteride for hair loss. Another user argues that drug response is unrelated to metabolism speed.
community 2020 updated guide for "I'm losing my hair, what do I do?". I've been taking Propecia for 12 years, and you can AMA.
Hair loss treatments discussed include Propecia, Rogaine, Nizoral shampoo, and dermarolling. Users shared experiences and results, with some noticing improvements in hair growth and maintenance.
community Wouldn’t it be funny if there already was a drug that existed which reactivated sleeping follicles? It would be our own version of Ozempic
PP405 shows promise for reactivating hair follicles, with potential maintenance using 5AR inhibitors. Current treatments like Minoxidil and finasteride are effective but have limitations, and there is hope for more effective solutions in the future.