Hair Keratin Pattern in Human Hair Follicles Grown In Vitro

April 2003 in “ Experimental dermatology ”

S. Thibaut, Christine Collin, Lutz Langbein, Jürgen Schweizer, Brigitte Gautier, Bruno Bernard

hair keratins hair follicles in vitro hair shaft keratinization morphology molecular organization

TLDR Human hair follicles grown in vitro maintain normal keratin patterns and structure.

This study investigated the expression and localization of human hair keratins in hair follicles grown in vitro for 10 days. The results showed that the in vitro growth did not alter the expression pattern of hair keratins, which were localized in specific compartments of the follicle, similar to in vivo conditions. The proper hair shaft keratinization process occurred, and the integrity of the hair follicle was maintained in terms of morphology and molecular organization.

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