Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes

    October 1998 in “ Journal of biological chemistry/˜The œJournal of biological chemistry ”
    Michael A. Rogers, Hermelita Winter, Christian Wolf … Jürgen Schweizer
    Studysummary This study discovered nine human type I hair keratin genes, including a transcribed pseudogene, in a 190 kbp genomic region, revealing three gene subclusters based on sequence homologies.
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    Research cited in this study 24

    1. A Variable Monilethrix Phenotype Associated With a Novel Mutation, Glu402Lys, in the Helix Termination Motif of the Type II Hair Keratin hHb1 Journal of Investigative Dermatology · 1998
    2. Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    3. A Splice Site Mutation in the Human Type I Hair Keratin Gene hHa1 Results in the Expression of a Tailless Keratin Isoform Journal of Biological Chemistry · 1997
    4. A New Mutation in the Type II Hair Cortex Keratin hHb1 Involved in the Inherited Hair Disorder Monilethrix Human Genetics · 1997
    5. Mutations in the Hair Cortex Keratin HHB6 Cause the Inherited Hair Disease Monilethrix Nature Genetics · 1997
    6. Sequences and Differential Expression of Three Novel Human Type-II Hair Keratins Differentiation · 1997
    7. Genomic Characterization of the Human Type I Cuticular Hair Keratin hHa2 and Identification of an Adjacent Novel Type I Hair Keratin Gene hHa5 Journal of Investigative Dermatology · 1996
    8. The Region Coding for the Helix Termination Motif and the Adjacent Intron 6 of the Human Type I Hair Keratin Gene hHa2 Contains Three Natural, Closely Spaced Polymorphic Sites Journal of Investigative Dermatology · 1996
    9. Sequence Data and Chromosomal Localization of Human Type I and Type II Hair Keratin Genes Experimental Cell Research · 1995
    10. A cDNA Encoding the Human Type I Hair Keratin hHa1 Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 1995
    11. A Novel Human Type I Hair Keratin Gene: Evidence For Two Keratin HHa3 Isoforms Molecular Biology Reports · 1995
    12. Sequence and Expression of Human Hair Keratin Genes Journal of Dermatological Science · 1994
    13. Sequence and Expression of Murine Type I Hair Keratins mHa2 and mHa3 Experimental Cell Research · 1994
    14. Characterization of a Hair (Wool) Keratin Intermediate Filament Gene Domain Journal of Investigative Dermatology · 1994
    15. Human Hair Keratins Journal of Investigative Dermatology · 1993
    16. Structural Features and Sites of Expression of a New Murine 65 kD and 48 kD Hair-Related Keratin Pair, Associated with a Special Type of Parakeratotic Epithelial Differentiation Differentiation · 1992
    17. Hair Follicle Differentiation: Expression, Structure, and Evolutionary Conservation of the Hair Type II Keratin Intermediate Filament Gene Family Development · 1992
    18. Hair-Specific Keratins: Characterization and Expression of a Mouse Type I Keratin Gene Journal of Investigative Dermatology · 1991
    19. Differential Expression of Type I Hair Keratins Journal of Investigative Dermatology · 1990
    20. Cloning And Characterization Of A Mouse Type I Hair Keratin cDNA Journal of Investigative Dermatology · 1988
    21. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues II: Concomitant and Mutually Exclusive Synthesis of Trichocytic and Epithelial Cytokeratins in Diverse Human and Bovine Tissues (Hair Follicle, Nail Bed and Matrix, Lingual Papilla, Thymic Reticulum) Differentiation · 1988
    22. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues: Human and Bovine Hair Follicles Differentiation · 1988
    23. Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    24. The Complement of Native Alpha-Keratin Polypeptides of Hair-Forming Cells: A Subset of Eight Polypeptides That Differ from Epithelial Cytokeratins Differentiation · 1986

    Related research 1

    1. Keratin 19: Predicted Amino Acid Sequence and Broad Tissue Distribution Suggest It Evolved from Keratinocyte Keratins Journal of Investigative Dermatology · 1989