TLDR Thyroid hormone receptor β1 is found in human hair follicles and helps them survive.
Researchers investigated the expression of thyroid hormone receptors (TRs) in human hair follicles and found that TRβ1 was the predominant form. Immunoreactive TRs were present in both dermal and epithelial compartments of the pilosebaceous unit. Additionally, they studied the effects of 3,3', 5-triiodo-L-thyronine (T3) on hair follicle survival in vitro and discovered that physiological levels of free T3 significantly enhanced hair follicle survival.
28 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal papilla cells are crucial for hair growth and can induce new hair follicles.
Thyroid problems can cause hair loss and change hair texture.
May 2024 in “Drug discovery today” Thyroid receptor β can help develop new drugs to treat hair loss.
1 citations,
January 2022 in “Springer eBooks” 106 citations,
January 2013 in “Clinical and Developmental Immunology” Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
9 citations,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
