Thyroid Receptor β: A Promising Target for Developing Novel Anti-Androgenetic Alopecia Drugs
May 2024
in “Drug discovery today”
TLDR Thyroid receptor β can help develop new drugs to treat hair loss.
Recent research indicates that thyroid receptor β (TRβ) agonists can activate hair follicles and stimulate hair growth, making TRβ a promising target for developing anti-androgenetic alopecia (AGA) drugs. This review details the mechanism of TRβ in treating AGA, summarizes advances in TRβ agonist candidates, and outlines the structure–activity relationships (SARs) of these agonists, aiming to aid in the development of effective anti-alopecia treatments.
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