Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics

    November 2021 in “ Journal of Cosmetic Dermatology
    Mark S Nestor, Glynis Ablon, Anita Gade, Haowei Han, Daniel A. Fischer
    TLDR Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.
    The document reviews various treatment options for androgenetic alopecia (AGA), focusing on their efficacy, side effects, compliance, financial considerations, and ethical issues. Treatments discussed include FDA-approved options like topical minoxidil and oral finasteride, as well as newer therapies like low-level light therapy, PRP, exosomes, and microneedling. Efficacy varies, with combination therapies often showing superior results. Side effects range from mild (e.g., scalp irritation) to severe (e.g., erectile dysfunction with finasteride). Compliance is crucial due to the chronic nature of AGA, and financial costs can be significant. Ethical considerations emphasize patient education and unbiased treatment recommendations. The document calls for more high-quality clinical trials to better compare treatment outcomes.
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