Post-Finasteride Syndrome: Risks and Side Effects of Finasteride for Androgenetic Alopecia

    March 2020 in “ Anais Brasileiros De Dermatologia ”
    Ana I. Pereira, Thamiris Lentz de Almeida Coelho
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    TLDR Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
    The document discusses the potential risks and side effects of using finasteride for the treatment of androgenetic alopecia (AAG), including post-finasteride syndrome (PFS), which can cause persistent sexual, neuropsychiatric, and physical symptoms even after discontinuing the drug. While some studies have shown a higher incidence of persistent side effects related to the use of finasteride, others have demonstrated the safety of the drug. The current literature data are controversial, and it is not yet possible to establish a causal relationship between 5α-reductase inhibitors and the persistence of sexual symptoms. The authors recommend that individuals considering finasteride for the treatment of AAG should be advised of these risks and should proceed with caution.
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      community Another clueless guy fearmongering and spreading misinformation

      in Chat  251 upvotes 1 year ago
      The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.

      community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

      in Research/Science  11 upvotes 5 months ago
      Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.

      community 1 month of using fin, so happy

      in Progress Pictures  863 upvotes 9 months ago
      User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 10 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 3 weeks ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

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