Finasteride-Induced Secondary Infertility Associated with Sperm DNA Damage

    February 2011 in “ Fertility and Sterility ”
    Hin Yu Vincent Tu, Armand Zini
    Studysummary This case report suggests that discontinuing low-dose finasteride in a 48-year-old man led to a significant reduction in sperm DNA fragmentation index, indicating a possible link between finasteride and sperm DNA damage.
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    Research cited in this study 3

    1. Propecia-Induced Spermatogenic Failure: A Report of Two Cases Fertility and Sterility · 2007
    2. The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men The Journal of Clinical Endocrinology and Metabolism · 2007
    3. Finasteride-Associated Male Infertility Revista do Hospital das Clínicas · 2004