81 citations
,
June 2014 in “American Journal of Men's Health” This study highlights that adverse effects from finasteride may persist in men after discontinuation, indicating a potential "post-finasteride syndrome.
2152 citations
,
November 2013 in “Urologia Internationalis” This study reviews the significant prevalence of organic etiologies, especially vascular causes, in erectile dysfunction among men under 40 and emphasizes thorough evaluation and consideration of treatment options like exercise and PDE-5 inhibitors.
73 citations
,
July 2013 in “The Journal of Sexual Medicine” This study observed that androgenic alopecia patients taking finasteride had altered neuroactive steroid levels and persistent depression symptoms even after stopping the treatment.
58 citations
,
September 2012 in “Dermatologic Clinics” This article reviews current knowledge on the causes, diagnosis, and medical treatments for androgenetic alopecia, particularly in men, and reports no new findings.
134 citations
,
August 2012 in “The Journal of Clinical Psychiatry” This study found that former finasteride users with persistent sexual side effects reported significantly higher rates of depressive symptoms and suicidal thoughts compared to controls.
12 citations
,
July 2012 in “Social Psychological and Personality Science” This research observed that men with shaved heads were perceived as more dominant, taller, and stronger than men with full hair, suggesting potential benefits in social perception.
21 citations
,
August 2011 in “Body Image” This study found that acceptance of hair loss is associated with lower psychological distress in young men, highlighting its adaptive role compared to compensation and avoidance strategies.
223 citations
,
December 2010 in “The Journal of Sexual Medicine” This review discusses persistent adverse effects of 5α‐reductase inhibitors, like diminished libido and erectile dysfunction, in some patients and highlights the need for patient discussions before therapy, especially for androgenetic alopecia.
22 citations
,
December 2010 in “Journal of Cosmetic Dermatology” The authors concluded that finasteride treatment inhibits hippocampal neurogenesis in mice, potentially impacting emotional behaviors and contributing to the pathophysiology of affective disorders.
99 citations
,
October 2006 in “BMC clinical pharmacology” This preliminary study suggests that finasteride might cause depressive symptoms, indicating the need for cautious prescription in patients at high risk for depression.
4 citations
,
July 2005 in “International Journal of Dermatology” This study found no significant difference in psychological stress between males with and without androgenetic alopecia. Social and cultural factors might influence perceptions of alopecia's impact.
174 citations
,
November 2002 in “Expert Reviews in Molecular Medicine” This review discusses the genetic factors contributing to androgenetic alopecia and highlights the potential for developing more effective therapies based on recent discoveries, but reports no new clinical results.
88 citations
,
October 2002 in “Journal of Dermatology” In this study, 19 patients treated with finasteride for androgenetic alopecia developed moderate to severe depression, which resolved after stopping the medication, suggesting an association between finasteride and mood disturbances.
18 citations
,
March 2000 in “PubMed” This study found that male pattern hair loss significantly negatively impacts men aged 18 to 40 in France, Italy, Germany, and the UK, with perceived noticeability contributing to these effects.
180 citations
,
September 1999 in “British Journal of Dermatology” This review discusses the psychological and social impacts of androgenetic alopecia and suggests that medical treatments can have some positive psychological effects, highlighting the condition's moderate stress and impact on body image.
192 citations
,
June 1992 in “Journal of The American Academy of Dermatology” Hair loss can cause low self-esteem, anxiety, and depression in men.
38 citations
,
January 1991 in “International Journal of Dermatology” In this study, men with androgenic alopecia taking minoxidil gel generally showed no evidence of psychological malfunction, but those over 35 experienced greater psychological improvement when they had cosmetic success with the treatment.
68 citations
,
February 1990 in “Journal of Applied Social Psychology” This study found that men with common male pattern baldness received less favorable initial social perceptions, including lower ratings of physical attractiveness, than their nonbalding counterparts.