Effectiveness and Safety of Low-Dose Oral Minoxidil in Male Androgenetic Alopecia

    Juan Jimenez-Cauhe, David Saceda-Corralo, Ana Rita Rodrigues-Barata, Ángela Hermosa-Gelbard, Oscar M. Moreno-Arrones, Diego Fernandez-Nieto, Sergio Vano-Galvan
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    TLDR Low-dose oral minoxidil effectively improves male hair loss with mild side effects.
    The study aimed to evaluate the effectiveness and safety of low-dose oral minoxidil (OM) in men with male androgenetic alopecia (MAA). A total of 41 men with a mean age of 33.3 years were included, and they received OM at a daily dose of 2.5 mg or 5 mg. Clinical improvement was observed in 37 patients (90.2%), with 11 of these patients (26.8%) presenting a marked improvement. Adverse effects were detected in 12 patients (29.3%), but all of the adverse effects were mild and well tolerated. OM at a dose of 5 mg daily was effective and presented an acceptable safety profile in the cohort of male patients with MAA.
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