A Randomized Controlled, Single-Observer Blinded Study to Determine the Efficacy of Topical Minoxidil Plus Microneedling Versus Topical Minoxidil Alone in the Treatment of Androgenetic Alopecia

    Muriki Naresh Kumar, Arun C Inamadar, Aparna Palit
    Studysummary This study found that combining microneedling with topical minoxidil was more effective than minoxidil alone in increasing hair count and improving patient satisfaction for men with androgenetic alopecia, though the cosmetic impact was not significant.
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    Research cited in this study 10

    1. Superiority of Dutasteride Over Finasteride in Hair Regrowth and Reversal of Miniaturization in Men With Androgenetic Alopecia: A Randomized Controlled Open-Label, Evaluator-Blinded Study Indian Journal of Dermatology, Venereology and Leprology · 2016
    2. Repeated Microneedle Stimulation Induces Enhanced Hair Growth in a Murine Model Annals of Dermatology · 2016
    3. Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy Indian Journal of Dermatology · 2015
    4. Androgenetic Alopecia: An Update Indian Journal of Dermatology, Venereology and Leprology · 2013
    5. A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study International Journal of Trichology · 2013
    6. Hair Follicle Stem Cell Differentiation Is Inhibited Through Cross-Talk Between Wnt/β-Catenin and Androgen Signaling in Dermal Papilla Cells From Patients With Androgenetic Alopecia British Journal of Dermatology · 2012
    7. Hair Regrowth Following a Wnt- and Follistatin-Containing Treatment: Safety and Efficacy in a First-in-Man Phase 1 Clinical Trial PubMed · 2011
    8. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    9. Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes Journal of Investigative Dermatology · 2007
    10. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004

    Related research 7

    1. Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil JAAD case reports · 2022
    2. The Efficacy of Topical Minoxidil for Non-Scarring Alopecia: A Systematic Review PubMed · 2019
    3. Disorders of Hair DeckerMed Medicine · 2013
    4. Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica Drugs · 1987
    5. Topical Minoxidil in the Treatment of Alopecia Areata Plastic & Reconstructive Surgery · 1985
    6. Alopecia Areata Treated With Topical Minoxidil Archives of Dermatology · 1984
    7. Topical Minoxidil in the Treatment of Alopecia Areata BMJ · 1983