Oral Bicalutamide for Female Pattern Hair Loss: A Pilot Study

October 2019 in “ Dermatologic Therapy ”

Diego Fernandez-Nieto, David Saceda-Corralo, Ana Rita Rodrigues-Barata, Ángela Hermosa-Gelbard, Oscar M. Moreno-Arrones, Juan Jimenez-Cauhe, Sergio Vano-Galvan

bicalutamide female pattern hair loss FPHL flutamide

Studysummary This source explores the potential use of oral bicalutamide for treating female pattern hair loss, but specific results or outcomes from the study are not reported in the abstract. Our plain-language summary of this paper — not a Tressless recommendation.

This pilot study evaluated the effectiveness and safety of bicalutamide in treating female pattern hair loss. The study found that bicalutamide presented an excellent safety profile and led to a great improvement in hair density in 53% of patients without significant adverse effects. The study suggests that bicalutamide might be a novel and useful therapeutic option for women with FPHL, with a better safety profile than flutamide.

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

3 / 3 results

Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial

research Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial

25 citations , December 2017 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that using an oral contraceptive with bicalutamide significantly reduced hirsutism in women with PCOS compared to an oral contraceptive alone, although it increased total cholesterol and LDL levels.

research Prospective Cohort Study on the Effects and Tolerability of Flutamide in Patients with Female Pattern Hair Loss

42 citations , April 2011 in “Annals of Pharmacotherapy”

This study found that long-term flutamide treatment reduced hair loss in women with female pattern hair loss, but liver-related dropouts were minimized at a very low dose of 62.5 mg/day.

research Treatment of Hyperandrogenic Alopecia in Women

108 citations , January 2003 in “Fertility and Sterility”

This study found that flutamide at 250 mg daily modestly improved hair thinning in premenopausal women with hyperandrogenic alopecia over one year, while cyproterone acetate and finasteride were not effective.