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Bicalutamide

Nonsteroidal anti-androgen, originally a prostate cancer drug

Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is primarily used to treat prostate cancer. It is typically used together with a gonadotropin-releasing hormone (GnRH) analogue or surgical removal of the testicles to treat metastatic prostate cancer (mPC). To a lesser extent, it is used at high doses for locally advanced prostate cancer (LAPC) as a monotherapy without castration. Bicalutamide was also previously used as monotherapy to treat localized prostate cancer (LPC), but authorization for this use was withdrawn following unfavorable trial findings. Besides prostate cancer, bicalutamide is limitedly used in the treatment of excessive hair growth and scalp hair loss in women, as a puberty blocker and component of feminizing hormone therapy for transgender girls and women, to treat gonadotropin-independent early puberty in boys, and to prevent overly long-lasting erections in men. It is taken by mouth.

Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

Research 10

  1. Bicalutamide: A potential new oral antiandrogenic drug for female pattern hair lossJournal of The American Academy of Dermatology · 2020 · 41 citations
  2. Bicalutamide in Dermatology: A Narrative ReviewIndian Dermatology Online Journal · 2024 · 3 citations
  3. Oral bicalutamide for female pattern hair loss: A pilot studyDermatologic Therapy · 2019 · 33 citations
  4. Bicalutamide: A reviewJournal of Cutaneous and Aesthetic Surgery · 2024 · 4 citations
  5. Mesotherapy with bicalutamide for female pattern hair lossIndian Journal of Dermatology Venereology and Leprology · 2024 · 4 citations
  6. Spironolactone versus Bicalutamide for Female Pattern Hair Loss: A 24-Month Unicenter Retrospective Comparative Study of Effectiveness and SafetyDermatology and Therapy · 2026
  7. Improvement of female pattern hair loss with bicalutamide: A time-dependent processJAAD International · 2025 · 2 citations
  8. The Hormonal Background of Hair Loss in Non-Scarring AlopeciasBiomedicines · 2024 · 36 citations
  9. Safety of oral bicalutamide in female pattern hair loss: A retrospective review of 316 patientsJournal of The American Academy of Dermatology · 2020 · 55 citations
  10. Combination of oral minoxidil and bicalutamide for the treatment of female pattern hair loss in adolescentsJournal of the American Academy of Dermatology · 2025 · 2 citations
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Posts 20

  1. How the FUCK do y'all afford 2.5mg dutasteride if you're in the euReddit · 16 Feb 2026
  2. treatment of Bicalutamide low dose weekly?Reddit · 27 Jun 2022
  3. Sending Dr. B dutasteride script to local pharmacy?Reddit · 30 Apr 2026
  4. Bicalutamide effect on androgens?Reddit · 20 Dec 2020
  5. If you had to take one, would it be dutasteride or oral minoxidil?Reddit · 2 Aug 2026
  6. 4 months progress I take 25 mg bicalutamide, estradiol patch, 5% liquid minoxidil twice daily and dermarolled once a week.Reddit · 31 Dec 2020
  7. 6 months on minoxidil shedding againReddit · 25 Mar 2026
  8. CAUTION: My Experience with RU58841Reddit · 17 Sept 2023
  9. Anyone tried Anagen “Smooth Release” oral minoxidil?Reddit · 19 Sept 2026
  10. Are there any men here who have taken bicalutamide without estradiol?Reddit · 20 Jul 2022
  11. RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etcReddit · 26 Feb 2024
  12. Fuck it, I’m ordering Pyri TopicalReddit · 18 Jul 2024
  13. Why isn't anybody on topical bicalutamide?Reddit · 16 Jun 2024
  14. Bicalutamide vs Dutasteride for hair growthReddit · 12 Jan 2022
  15. Seriously concerning sides effects occurring on RU58841Reddit · 21 Dec 2020
  16. [Research/Science] What's the General Consensus On RU58841?Reddit · 4 Jun 2023
  17. Bicalutamide in men ¿does it helps with recovering?Reddit · 28 Jun 2022
  18. Bicalutamide hair thickenningReddit · 16 Feb 2021
  19. Topical bicalutamide after fin/dut?Reddit · 18 Jul 2020
  20. Thinking of crushing bicalutamide/spiro or any other test suppressant in my topical fin min mix. What do yall think?Reddit · 27 Jun 2023
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