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    Bicalutamide

    Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is primarily used to treat prostate cancer. It is typically used together with a gonadotropin-releasing hormone (GnRH) analogue or surgical removal of the testicles to treat metastatic prostate cancer (mPC). To a lesser extent, it is used at high doses for locally advanced prostate cancer (LAPC) as a monotherapy without castration. Bicalutamide was also previously used as monotherapy to treat localized prostate cancer (LPC), but authorization for this use was withdrawn following unfavorable trial findings. Besides prostate cancer, bicalutamide is limitedly used in the treatment of excessive hair growth and scalp hair loss in women, as a puberty blocker and component of feminizing hormone therapy for transgender girls and women, to treat gonadotropin-independent early puberty in boys, and to prevent overly long-lasting erections in men. It is taken by mouth.

    Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

    Research 10

    1. Efficacy and tolerability of oral bicalutamide in forty postmenopausal women with female pattern hair loss: a retrospective study Actas Dermo-Sifiliográficas · 2025
    2. Unexpected Hair Regrowth Following Oral Bicalutamide Exposure in a Male Patient With Androgenetic Alopecia and a Suboptimal Response to Conventional Therapies: A Case Report Cureus · 2026
    3. Efficacy and safety of bicalutamide in female hair loss: a review of the literature JAAD reviews. · 2025
    4. Bicalutamide: A potential new oral anti-androgenic drug for female pattern hair loss - A case series Cosmoderma · 2026
    5. Mesotherapy with bicalutamide for female pattern hair loss Indian Journal of Dermatology Venereology and Leprology · 2024
    6. Bioavailability File: Bicalutamide Fabad Journal of Pharmaceutical Sciences · 2025
    7. Spironolactone versus Bicalutamide for Female Pattern Hair Loss: A 24-Month Unicenter Retrospective Comparative Study of Effectiveness and Safety Dermatology and Therapy · 2026
    8. Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial The Journal of Clinical Endocrinology & Metabolism · 2017 · 25 citations
    9. Response to “Improvement of female pattern hair loss with bicalutamide: a time-dependent process” JAAD International · 2025
    10. Improvement of female pattern hair loss with bicalutamide: a time-dependent process JAAD International · 2025
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    Community 10

    1. Can I take bicalutamide for hair loss as a man, but don’t want to transition? Reddit · 21 Mar 2026
    2. Bicalutamide vs Finasteride for female AGA plus TE Reddit · 25 Feb 2026
    3. Topical bicalutamide vs ru58841 Reddit · 2 Sept 2024
    4. Anyone here used spirolactone/cyproterone acetate/bicalutamide? Reddit · 8 Sept 2025
    5. Why isn't anybody on topical bicalutamide? Reddit · 16 Jun 2024
    6. Are there any men here who have taken bicalutamide without estradiol? Reddit · 20 Jul 2022
    7. Does anyone take bicalutamide for fphl? If so which dose Reddit · 7 Sept 2022
    8. Bicalutamide for hair loss Reddit · 7 Dec 2020
    9. Bicalutamide effect on androgens? Reddit · 20 Dec 2020
    10. Does anyone have any experience with Estradiol, Cyproterone Acetate, Spironolactone, Bicalutamide ? Reddit · 24 Nov 2019
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