Efficacy and Safety of Spironolactone Versus Bicalutamide in Female Pattern Hair Loss: A Retrospective Comparative Study

    Ayushi Jha, Md Zeeshan, Anupama Singh, Anupama Singh
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    TLDR Bicalutamide is more effective and safer than spironolactone for treating female hair loss.
    This retrospective study compared the efficacy and safety of spironolactone and bicalutamide in treating female pattern hair loss (FPHL) in 120 women aged 18-50. Patients were divided into two groups: one taking 100 mg of spironolactone daily and the other taking 50 mg of bicalutamide daily, both with topical minoxidil 2%. After 24 weeks, the bicalutamide group showed a significantly greater reduction in hair loss severity (28.20%) compared to the spironolactone group (19.51%). Global photographic assessments also indicated more marked improvement in the bicalutamide group. Despite the study's retrospective nature and small sample size, bicalutamide demonstrated greater efficacy and a better safety profile than spironolactone for FPHL treatment.
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      community bicalutamide or spironolactone for fphl

      in Female  6 upvotes 2 years ago
      Bicalutamide and spironolactone are being compared for their effectiveness and safety in treating female pattern hair loss. The conversation seeks advice on which is better to use.

      community Spironolactone or bicalutamide prescription

      in Treatment  4 upvotes 1 year ago
      The conversation is about someone seeking a doctor in the EU who prescribes spironolactone or bicalutamide for female pattern hair loss, as they are having difficulty finding treatment options beyond Minoxidil in Austria. They are asking for recommendations and are open to direct messages for assistance.

      community C’est terrible - at my wits end

      in Female  443 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Goodbye y'all, it's been a journey but have accepted where I'm at

      in Update  219 upvotes 1 year ago
      The conclusion of this conversation about hair loss is that the user, y00sh420, tried various treatments including a $700 lllt helmet, topical minoxidil and finasteride, spectraDNC, and micro needling, but did not achieve the desired results. They have decided to stop trying until a cure for male pattern baldness is found. Other users expressed different opinions on hair loss treatments.

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