Faculty Opinions Recommendation of Mesotherapy with Bicalutamide: A New Treatment for Androgenetic Alopecia

    Juan Ferrando, José M Mir-Bonafé, Andrea Combalía
    From the encyclopedia
    Bicalutamide →

    a nonsteroidal anti-androgen, most commonly used orally for women

    Mesotherapy →

    technique to inject very small amounts of beneficial chemicals into the scalp

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    Studysummary Bicalutamide mesotherapy improved hair density in women with hair loss and was well received.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The document discusses a novel study where six premenopausal women with Female pattern hair loss (FPHL) were treated with bicalutamide mesotherapy. The patients, with a mean age of 35.7 years and diagnosed with Olsen Grade II or III alopecia, underwent three monthly sessions of 1ml bicalutamide 0.5% mesotherapy. Clinical images taken at baseline, after the third session, and 6 months post-first session were evaluated by two independent dermatologists. The study found an improvement in hair density after the third session, but the degree of alopecia remained unchanged. All patients reported improved hair density and seborrhea after 3 months of treatment, with an overall satisfaction score of 6.3. The study concluded that bicalutamide mesotherapy was well tolerated and welcomed by the patients.
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