Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients

    Sergio Vano-Galvan, Rodrigo Pirmez, Ángela Hermosa-Gelbard, Oscar M. Moreno-Arrones, David Saceda-Corralo, Ana Rita Rodrigues-Barata, Juan Jimenez-Cauhe, Wei Choon Alvin Koh, Janina Eliza Poa, Rebekka Jerjen, Lara Trindade de Carvalho, Jared Marc John, Corina Isabel Salas-Callo, Colombina Vincenzi, Lu Yin, Kristen LoSicco, Anna Waskiel-Burnat, Michela Starace, José Luis Zamorano, Pedro Jaén-Olasolo, Bianca Maria Piraccini, Lidia Rudnicka, Jerry Shapiro, Antonella Tosti, Rodney Sinclair, Bevin Bhoyrul
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    TLDR Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.
    A study of 1404 patients found that low-dose oral minoxidil is a safe and effective treatment for hair loss, with hypertrichosis being the most common side effect. Systemic adverse effects were rare, with lightheadedness reported in 1.7% of patients and fluid retention in 0.6%. Treatment was discontinued in 1.7% of patients due to adverse effects. The study suggests that low-dose oral minoxidil is a safe treatment option for hair loss.
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