Efficacy of Intralesional and Oral Dutasteride in the Treatment of Androgenetic Alopecia: A Systematic Review

January 2020 in “ Skin appendage disorders ”

Maira Elizabeth Herz-Ruelas, Neri Alejandro Álvarez-Villalobos, Juan Manuel Millán-Alanís, Humberto de Leon-Gutierrez, Jorge Ocampo-Candiani, Minerva Gómez-Flores, Ramon Grimalt

dutasteride oral dutasteride intralesional dutasteride androgenetic alopecia systemic treatment sexual adverse events Avodart

TLDR Oral dutasteride works better for hair loss, but has more sexual side effects; intralesional dutasteride is a possible alternative.

This systematic review analyzed the efficacy and safety of intralesional and oral dutasteride in treating androgenetic alopecia. The study found that both treatments were effective, but oral dutasteride appeared to be more effective than intralesional dutasteride. However, oral dutasteride had more reported sexual adverse events. Intralesional dutasteride may be a feasible alternative for those unwilling to receive systemic treatment, but more clinical trials evaluating its efficacy and safety are needed.

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Research cited in this study

13 / 13 results

research Prospective Randomized Study of Sexual Function in Men Taking Dutasteride for the Treatment of Androgenetic Alopecia

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Dutasteride safely treats hair loss without harming sexual function.

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151 citations, August 2010 in “British Journal of Dermatology”

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research Dutasteride Improves Male Pattern Hair Loss in a Randomized Study in Identical Twins

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research Prevalence of Male and Female Pattern Hair Loss in Maryborough

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Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.

research The Genetics of Androgenetic Alopecia

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Too much androgen can cause hair loss; finasteride may help.

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Androgens can cause hair growth in some areas and hair loss on the scalp.

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Dutasteride successfully treated a woman's hair loss when other treatments failed.

research Finasteride in the Treatment of Androgenetic Alopecia

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research Current Management of Androgenetic Alopecia in Men

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Efficacy of Intralesional and Oral Dutasteride in the Treatment of Androgenetic Alopecia: A Systematic Review

Research cited in this study

research Prospective Randomized Study of Sexual Function in Men Taking Dutasteride for the Treatment of Androgenetic Alopecia

research Long-Term Safety and Efficacy of Dutasteride in the Treatment of Male Patients with Androgenetic Alopecia

research A Randomized, Active- and Placebo-Controlled Study of the Efficacy and Safety of Different Doses of Dutasteride Versus Placebo and Finasteride in the Treatment of Male Subjects with Androgenetic Alopecia

research Evaluation of the Effect of Injection of Dutasteride as a Mesotherapeutic Tool in the Treatment of Androgenetic Alopecia in Males

research S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents

research Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study

research Medical Treatments for Male and Female Pattern Hair Loss

research Dutasteride Improves Male Pattern Hair Loss in a Randomized Study in Identical Twins

research Prevalence of Male and Female Pattern Hair Loss in Maryborough

research The Genetics of Androgenetic Alopecia

research Androgenetic Alopecia and Microinflammation

research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia

research Androgens and Human Hair Growth

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