Two Cases of Paradoxical Nonscarring Alopecia After Mesotherapy with Dutasteride

    August 2021 in “ Skin appendage disorders ”
    Leandra Reguero del Cura, Adrian De Quintana Sancho, Marta Millan Lombraña, Ana Elisabet López Sundh, Marcos Pérez López
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    TLDR Two people lost hair unexpectedly after getting a common hair loss treatment with a drug called Dutasteride.
    The document presents two cases of paradoxical nonscarring alopecia following mesotherapy with dutasteride, a treatment for hair fall that involves microinjection of the drug into the dermis. Dutasteride is a second-generation 5a-reductase enzyme inhibitor that decreases serum dihydrotestosterone levels by 90%. It inhibits both type 1 and 2 enzymes, while finasteride inhibits only type 2. While mesotherapy with dutasteride is becoming increasingly common and usually has only mild transitory side effects at the injection site, these two cases (one male and one female with androgenetic alopecia) developed patchy alopecia after treatment. One of them also developed skin atrophy on the affected areas without improvement at short term follow-up. These cases highlight the potential paradoxical side effects of mesotherapy as a therapeutic technique for hair loss.
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      community How is there still no consensus on Topical Dutasteride in 2024?

      in Finasteride/Dutasteride  149 upvotes 6 months ago
      The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.

      community What is your opinion on Dutasteride Mesotherapy

      in Treatment  13 upvotes 1 month ago
      Dutasteride mesotherapy was not effective for hair regrowth, leading to consideration of oral or topical dutasteride. Oral dutasteride is suggested as more effective and cost-efficient than mesotherapy, with some users experiencing side effects from finasteride.

      community Dutasteride Mesotherapy in Toronto

      in Treatment  6 upvotes 4 months ago
      A user is seeking information on clinics in Toronto offering dutasteride mesotherapy as an alternative to oral dutasteride while trying to conceive. They are looking for recommendations and information.

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