TLDR Mesotherapy is generally safe but can cause adverse reactions due to its varied use and lack of standardization; individualized treatment is needed for these complications.
The review article "Mesotherapy: Safety profile and management of complications" from 2019 analyzed articles published between 1992 and 2018 to summarize complications related to mesotherapy, a procedure that involves injecting active substances into the dermis and subcutaneous tissue to treat various local medical and cosmetic conditions. Despite being considered relatively safe, the study found that a range of adverse reactions can occur due to the procedure's wide application and lack of standardization. The management of these complications was found to be mostly individualized. The authors concluded that larger systematic studies are needed to adequately evaluate the safety profile of mesotherapy and to determine standardized therapy parameters to minimize the risk of potential adverse reactions.
23 citations,
October 2018 in “Expert Opinion on Drug Safety” Consider benefits and risks of new alopecia treatments for safety.
6 citations,
November 2017 in “Journal of the European Academy of Dermatology and Venereology” A woman got melanoma on her scalp after anti-hair loss treatment with injections.
18 citations,
February 2017 in “Journal of Cosmetic Dermatology” Mesotherapy for hair loss can sometimes cause more hair loss and scarring.
41 citations,
April 2012 in “Journal of The European Academy of Dermatology and Venereology” Dutasteride-containing mesotherapy effectively treats female hair loss, improving density and thickness with minimal side effects.
14 citations,
January 2012 in “International Journal of Dermatology” A woman got a rare condition called oleoma after cellulite treatment, which left scars even after treatment.
49 citations,
July 2009 in “Journal of the American Academy of Dermatology” Some people experienced hair loss after mesotherapy treatments for hair loss.
October 2021 in “Cosmoderma” Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.
14 citations,
January 2012 in “International Journal of Dermatology” A woman got a rare condition called oleoma after cellulite treatment, which left scars even after treatment.
1 citations,
October 2010 in “Series in cosmetic and laser therapy” Mesotherapy is a minimally invasive treatment with potential benefits and risks, requiring standardized practices and further investigation.
23 citations,
November 2007 in “Journal of cosmetic dermatology” Both mesotherapy treatments reduced under-chin fat equally and were safe with mild side effects.
1 citations,
December 2023 in “Life” PRP helps skin heal, possibly through special cells called telocytes.