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research Oral finasteride use and sexual adverse events: signal detection from disproportionality analyses of data from the United States Food and Drug Administration Adverse Event Reporting System

January 2026 in “Journal of Dermatological Treatment”

The researchers reported that oral finasteride 1 mg was associated with more frequent reports of sexual adverse events than dutasteride 0.5 mg, particularly after 2012, which may be influenced by the nocebo effect.

research Long-term treatment with finasteride: sexual adverse events and fracture rates

January 2002 in “European Urology Supplements”

Finasteride can cause sexual side effects like decreased libido and erectile dysfunction.

research Sexual adverse events-related to dutasteride e finasteride: analysis of real-life data from Eudra-Vigilance database

October 2021 in “European urology open science”

research Risk assessment of the top 60 drugs for drug-related sexual dysfunction: a disproportion analysis from the Food and Drug Administration adverse event reporting system

August 2025 in “The Journal of Sexual Medicine”

This retrospective pharmacovigilance study identified 34 drugs, including finasteride and dutasteride, that may be associated with sexual dysfunction, with a higher risk observed in males aged 31-45.

Comments Concerning the Real Risk of Sexual Adverse Events Secondary to the Use of 5-Alpha-Reductase Inhibitors

research Comments concerning the real risk of sexual adverse events secondary to the use of 5-ARIs

January 2016 in “Archivio italiano di urologia, andrologia”

This article reviews treatment-induced sexual dysfunctions related to 5-alpha-reductase inhibitors and reports no new results; it highlights the need to better define and understand this controversial topic.

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community GT20029 - Promising phase II results

16 upvotes 2 years ago

GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

community 5ARi of choice not working yet? Paper Review for efficacy + safety

in Research/Science 14 upvotes 7 months ago

Dutasteride is more effective than finasteride for hair loss, especially at the crown and midscalp, but both have similar side-effect profiles with low incidence of sexual adverse events. Improvement is measured visually, and significant results may take over 12 months to appear.

community Debunking the "Adverse metabolic consequences of dutasteride"

in Research/Science 44 upvotes 5 years ago

Dutasteride is more effective than finasteride, has neuroprotective benefits, and may prevent acne. Despite initial concerns about metabolic effects, further research suggests it is safe for most users, especially if not hypogonadal.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

192 upvotes 4 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community Thoughts on Finasteride and Sexual Side Effects

52 upvotes 7 years ago

A user discusses starting finasteride for hair loss despite concerns about potential sexual side effects, emphasizing the psychological factors involved. Other users share mixed experiences, with some reporting no side effects and others experiencing issues.

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