Dutasteride Improves Male Pattern Hair Loss in a Randomized Study in Identical Twins

March 2007 in “ Journal of Cosmetic Dermatology ”

Dow Stough

dutasteride male pattern hair loss MPHL placebo scalp hair growth hair count patient self-assessment hair growth questionnaire Avodart

Studysummary This study in identical twin males with androgenetic alopecia found that dutasteride significantly improved hair growth compared to placebo over one year.

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The study investigated the effectiveness of dutasteride in treating male pattern hair loss (MPHL) in identical twins. The study found that treatment with dutasteride slowed the progression of hair loss and enhanced hair growth compared to treatment with placebo. The study supports previously published trials showing that dutasteride significantly improves scalp hair growth based on assessments of standardized clinical photographs, hair count, and patients' assessments of their scalp hair. The validated patient self-assessment hair growth questionnaire demonstrated that treatment with dutasteride, in comparison to placebo, led to improvement in patients' scalp hair growth and increased satisfaction with the appearance of hair.

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Research cited in this study

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The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride

research The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride

215 citations , November 2006 in “Journal of The American Academy of Dermatology”

This study found that dutasteride increased scalp hair growth in men with male pattern hair loss, particularly at a 2.5 mg dose, and was more effective than finasteride over 24 weeks.

research Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia

129 citations , October 2000 in “British Journal of Dermatology”

This study found that finasteride increases anagen hair growth in men with androgenetic alopecia.

research The Effects of Finasteride on Scalp Skin and Serum Androgen Levels in Men with Androgenetic Alopecia

12 citations , October 1999 in “Journal of The American Academy of Dermatology”

research Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss

187 citations , June 1999 in “Journal of The American Academy of Dermatology”

This study reported that finasteride 1 mg/day significantly increased hair growth and slowed hair loss in men with frontal scalp hair thinning over one year, and these benefits continued or improved in the second year.

research Finasteride

125 citations , January 1999 in “Drugs”

This study found that oral finasteride 1 mg/day promotes hair growth and prevents further hair loss in a significant proportion of men with male pattern hair loss over two years.

Finasteride in the Treatment of Men with Androgenetic Alopecia

research The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients With Male Pattern Baldness

61 citations , September 1994 in “The Journal of Clinical Endocrinology and Metabolism”