Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation
August 2008
in “
The Journal of Clinical Endocrinology & Metabolism
”
thyroid hormones T3 T4 anagen phase hair matrix keratinocytes apoptosis TGF-B2 melanin synthesis deiodinase genes hair follicle cycling keratin expression triiodothyronine thyroxine growth phase cell death transforming growth factor beta 2 pigment production enzyme genes hair growth cycle protein expression
Studysummary In this study, T3 and T4 were found to directly influence human hair follicles in vitro, enhancing keratinocyte proliferation, prolonging the hair growth phase, and affecting pigmentation.
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