Human Hair Growth In Vitro: A Model for the Study of Hair Follicle Biology

    July 1994 in “ Journal of Dermatological Science ”
    Michael P. Philpott, Deborah A. Sanders, Gillian E. Westgate, Terence Kealey
    Studysummary In this study, the researchers developed an in vitro model that maintains human hair follicles to grow at in vivo rates and observed that factors like EGF and IGF-I influence hair follicle growth and catagen entry.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jdsjournal.com →
    Discuss this study in the Community →

    Research cited in this study 24

    1. Prolonged Maintenance of Human Hair Follicles In Vitro in a Serum-Free Medium British Journal of Dermatology · 1993
    2. Enhanced In Vitro Hair Growth at the Air-Liquid Interface: Minoxidil Preserves the Root Sheath in Cultured Whisker Follicles In Vitro Cellular & Developmental Biology - Animal · 1993
    3. Metabolism of Freshly Isolated Human Hair Follicles Capable of Hair Elongation: A Glutaminolytic, Aerobic Glycolytic Tissue Journal of Investigative Dermatology · 1993
    4. Organ Culture of Human Hair Follicles in Serum-Free Medium Archives of Dermatological Research · 1993
    5. Rat Hair Follicle Growth In Vitro British Journal of Dermatology · 1992
    6. Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp Journal of Endocrinology/Journal of endocrinology · 1992
    7. Hair Growth Induction: Roles of Growth Factors Annals of the New York Academy of Sciences · 1991
    8. An In Vitro Model for the Study of Human Hair Growth Annals of the New York Academy of Sciences · 1991
    9. Inductive Properties of Hair Follicle Cells Annals of the New York Academy of Sciences · 1991
    10. TGF-Alpha Is Widely Expressed in Differentiated as Well as Hyperproliferative Skin Epithelium Journal of Investigative Dermatology · 1991
    11. Human Hair Growth In Vitro Journal of Cell Science · 1990
    12. Mode of Action of Mouse Epidermal Growth Factor on the Wool Follicles of Merino Sheep: An Ultrastructural Study Australian Journal of Agricultural Research · 1989
    13. Studies on the Biochemistry and Morphology of Freshly Isolated and Maintained Rat Hair Follicles Journal of Cell Science · 1989
    14. Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture Journal of Investigative Dermatology · 1989
    15. Effects of Intradermally Injected and Topically Applied Mouse Epidermal Growth Factor on Wool Growth, Skin, and Wool Follicles of Merino Sheep Australian Journal of Biological Sciences · 1988
    16. Cultivation of Murine Hair Follicles as Organoids in a Collagen Matrix Journal of Investigative Dermatology · 1987
    17. Cyclosporin A Stimulates Hair Growth in Nude Mice PubMed · 1987
    18. Differences in Human Skin Between the Epidermal Growth Factor Receptor Distribution Detected by EGF Binding and Monoclonal Antibody Recognition Journal of Investigative Dermatology · 1985
    19. Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal Appendages Journal of Investigative Dermatology · 1984
    20. Distribution of Epidermal Growth Factor Receptors in Rat Tissues During Embryonic Skin Development, Hair Formation, and the Adult Hair Growth Cycle Journal of Investigative Dermatology · 1984
    21. Effects of Epidermal Growth Factor on Hair Growth in the Mouse Journal of Endocrinology · 1981
    22. In Vitro Growth of Postembryonic Hair Journal of Investigative Dermatology · 1973
    23. Morphogenesis of the Hair Follicle During Catagen Cell and Tissue Research · 1970
    24. Role of Macrophages in Collagen Resorption During Hair Growth Cycle Journal of Ultrastructure Research · 1969

    Related research 3

    1. Progenic Hair Regrowth Treatment: The Use of Platelet-Released Growth Factors for Treating Androgenetic Alopecia by Activating Hair Follicle Stem Cells Journal of clinical & experimental dermatology research · 2014
    2. Fullerene Nanomaterials Potentiate Hair Growth Nanomedicine · 2009
    3. Substance P Prolongs Human Hair Growth In Vitro Journal of dermatological science · 2003