Substance P Prolongs Human Hair Growth In Vitro

September 2003 in “ Journal of dermatological science ”

Won Soo Lee, In Bum Sohn

substance P hair growth organ culture method hair follicles proliferation

Studysummary This study investigated the effects of substance P on human hair growth but found its role in hair follicle physiology remains unclear. Our plain-language summary of this paper — not a Tressless recommendation.

The study investigated the role of substance P (SP) on human hair growth using an organ culture method. It was found that SP prolonged the duration of hair growth and increased the rate of linear hair growth. This suggested that SP might play a significant role in the physiology of hair follicles by promoting their proliferation. The findings provided insights into the potential of SP as a therapeutic target for hair growth regulation.

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research Whole Hair Follicle Culture

57 citations , October 1996 in “Dermatologic clinics”

This study found that using hyaluronic acid microneedles to deliver minoxidil significantly reduced hair loss in chemotherapy-induced alopecia mice, with only 10% of the dose used in topical applications.