TLDR HA-MNs with MXD effectively treat hair loss better than topical MXD with fewer side effects.
The document discussed the in vitro culture of whole hair follicles, highlighting that while embryonic hair follicles could initially sustain hair growth in isolated skin plugs, this ability diminished with time and the age of the embryo. Postembryonic hair follicle growth was also studied, showing responsiveness to exogenous growth factors. The successful culture of hair follicles required careful isolation to avoid damage, using methods like shearing and microdissection. The study emphasized the potential of cultured hair follicles as a model system to explore hair biology and the mechanisms controlling hair growth, suggesting further in vitro and in vivo studies. The research was funded by Unilever and acknowledged contributions from several individuals and sources.
27 citations,
September 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” Small amounts of Vitamin D3 can boost hair growth, but too much can stop it.
124 citations,
August 1994 in “Journal of Investigative Dermatology” Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.
94 citations,
February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” EGF makes hair follicles grow longer but stops hair production.
20 citations,
February 1994 in “In vitro cellular & developmental biology. Animal” Wool follicles can grow in a lab with the right nutrients and conditions.
25 citations,
August 1992 in “In vitro cellular & developmental biology” The new system can grow hair in the lab and test hair growth treatments.
34 citations,
December 1991 in “Annals of the New York Academy of Sciences” The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
121 citations,
March 1989 in “Journal of Investigative Dermatology” Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.
January 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” Minoxidil can effectively treat patchy hair loss by stimulating hair growth.
