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research The Biology of Hair Follicles

1113 citations , August 1999 in “The New England Journal of Medicine”

This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.

research Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

990 citations , October 1999 in “Development”

This study found that LEF1/TCF3 is necessary but not sufficient for TOPGAL activation in hair follicle development, indicating complex regulation in the skin.

research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells

949 citations , January 2001 in “Cell”

This study demonstrated that multipotent stem cells in adult mice whisker follicles migrate to produce whisker growth, and that this process requires precise control of stem cell trafficking.

research Molecular Mechanisms Regulating Hair Follicle Development

854 citations , February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

This review summarizes recent advances in understanding the molecular mechanisms of hair follicle formation and discusses potential future clinical applications for treating hair loss and skin tumors, but it reports no new clinical results.

research Lgr5 marks cycling, yet long-lived, hair follicle stem cells

835 citations , October 2008 in “Nature Genetics”

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

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Community Join

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community 4 years wearing hair systems - what nobody tells you when you start

227 upvotes 6 months ago

Hair systems require frequent maintenance and can be costly, but a DIY approach with bi-weekly changes can help manage these issues. Minoxidil and finasteride were tried but not consistently used due to side effects and personal preferences.

community Has Anyone Lost Morning Erections Due to Finasteride & Got Them Back?

in Chat 58 upvotes 1 year ago

Finasteride can cause sexual side effects like reduced libido and weaker erections, but experiences vary. Some users switch to dutasteride or topical treatments, while others stop finasteride to restore normal sexual function.

community hairloss in my 20s has ruined my life.

in Research/Science 373 upvotes 1 year ago

A person in their 20s is struggling with hair loss, using treatments like minoxidil and finasteride. Suggestions include self-improvement, therapy, hair transplants, and focusing on acceptance and confidence.

community Hair Systems ... they work

27 upvotes 5 years ago

Hair systems are effective for hair loss, offering benefits over treatments like finasteride. Personal choice and confidence in appearance are emphasized.

community A practical checklist for comparing hair transplant clinics before deciding

in Hair Transplants 107 upvotes 4 days ago

When comparing hair transplant clinics, consider factors beyond price and graft count, such as surgeon involvement, donor area assessment, technique, aftercare, and what's included in the price. Use a checklist to evaluate clinics and avoid pressure tactics or vague information.

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learn Hair Transplant

Is a hair transplant painful? Clinics say local anaesthetic makes the procedure itself mostly comfortable, but the anaesthetic injections sting and soreness for a few days afterwards is common. Pain varies from person to person.
What are the risks and side effects of a hair transplant? Reported risks include swelling, redness, folliculitis, numbness, infection, scarring and temporary shock loss; less often skin necrosis, poor graft growth or over-harvesting of the donor area.
Will transplanted hair fall out after a hair transplant? Transplanted hair usually lasts long term, although some grafts may not survive and hair around them can keep thinning. Shedding of the transplanted hairs in the first weeks is normal.
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