Keratinocyte Differentiation in Psoriatic Scalp: Morphology and Expression of Epithelial Keratins

    July 2006 in “ British Journal of Dermatology ”
    Caroline Wilson, D. Dean, E. Birgitte Lane … Irene M. Leigh
    Studysummary This study found that keratin K17 is induced in the suprabasal layer of psoriatic scalp epidermis during epidermal hyperproliferation, suggesting it is not specific to hair follicles.
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    Research cited in this study 9

    1. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989
    2. Keratin 19: Predicted Amino Acid Sequence and Broad Tissue Distribution Suggest It Evolved from Keratinocyte Keratins Journal of Investigative Dermatology · 1989
    3. A Morphometric and Histologic Study of the Scalp in Psoriasis: Paradoxical Sebaceous Gland Atrophy and Decreased Hair Shaft Diameters Without Alopecia PubMed · 1989
    4. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues Differentiation · 1988
    5. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues: Human and Bovine Hair Follicles Differentiation · 1988
    6. Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    7. The Complement of Native Alpha-Keratin Polypeptides of Hair-Forming Cells: A Subset of Eight Polypeptides That Differ from Epithelial Cytokeratins Differentiation · 1986
    8. The In Vitro Properties of Dermal Papilla Cell Lines Established From Human Hair Follicles British Journal of Dermatology · 1986
    9. Different Keratin Polypeptides in Epidermis and Other Epithelia of Human Skin: A Specific Cytokeratin of Molecular Weight 46,000 in Epithelia of the Pilosebaceous Tract and Basal Cell Epitheliomas The Journal of Cell Biology · 1982

    Related research 9

    1. Expression of Caspase-14 and Keratin-19 in the Human Epidermis and Appendages During Fetal Skin Development Archives of Dermatological Research · 2013
    2. Keratinocyte Differentiation in Psoriatic Scalp: Morphology and Expression of Epithelial Keratins British Journal of Dermatology · 2006
    3. Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia ˜The œAmerican journal of pathology · 2000
    4. The Insulin-Like Growth Factor 1 Receptor Is Expressed by Epithelial Cells with Proliferative Potential in Human Epidermis and Skin Appendages: Correlation of Increased Expression with Epidermal Hyperplasia Journal of Investigative Dermatology · 1996
    5. Solid Basal Cell Epithelioma Possibly Originates From the Outer Root Sheath of the Hair Follicle PubMed · 1993
    6. Epidermis Reconstructed from the Outer Root Sheath of Human Hair Follicle: Effect of Retinoic Acid Archives of Dermatological Research · 1993
    7. Architecture of Reconstructed Epidermis on Collagen Lattices Varies According to the Method Used: A Comparative Study Skin Pharmacology and Physiology · 1990
    8. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989
    9. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987