Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation

    November 1989 in “ The Journal of Cell Biology ”
    Pierre A. Coulombe, Raphael Kopan, Elaine Fuchs
    Studysummary This study reported that K14 expression patterns and keratin filament organization in human skin's hair follicles differ from those in the epidermis, indicating distinct differentiation programs.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on rupress.org →
    Discuss this study in the Community →

    Research cited in this study 14

    1. Keratin 19: Predicted Amino Acid Sequence and Broad Tissue Distribution Suggest It Evolved from Keratinocyte Keratins Journal of Investigative Dermatology · 1989
    2. A New Look Into an Old Problem: Keratins as Tools to Investigate Determination, Morphogenesis, and Differentiation in Skin Genes & Development · 1989
    3. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues Differentiation · 1988
    4. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues II: Concomitant and Mutually Exclusive Synthesis of Trichocytic and Epithelial Cytokeratins in Diverse Human and Bovine Tissues (Hair Follicle, Nail Bed and Matrix, Lingual Papilla, Thymic Reticulum) Differentiation · 1988
    5. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues: Human and Bovine Hair Follicles Differentiation · 1988
    6. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987
    7. Chapter 2: The Human Keratin Genes and Their Differential Expression Current topics in developmental biology/Current Topics in Developmental Biology · 1987
    8. Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    9. Differential Expression of Keratin 19 in Normal Human Epithelial Tissues Revealed by Monospecific Monoclonal Antibodies The Histochemical Journal · 1986
    10. The Complement of Native Alpha-Keratin Polypeptides of Hair-Forming Cells: A Subset of Eight Polypeptides That Differ from Epithelial Cytokeratins Differentiation · 1986
    11. Cell Differentiation in Human Anagen Hair and Hair Follicles Studied with Anti-Hair Keratin Monoclonal Antibodies Journal of Investigative Dermatology · 1986
    12. Outer Root Sheath Keratinization in Anagen and Catagen of the Mammalian Hair Follicle: A Seventh Distinct Type of Keratinization in the Hair Follicle - Trichilemmal Keratinization PubMed · 1981
    13. Structural Features of the Alpha-Type Filaments of the Inner Root Sheath Cells of the Guinea Pig Hair Follicle Biochemistry · 1978
    14. Characterization of the Proteins of Guinea-Pig Hair and Hair-Follicle Tissue Biochemical Journal · 1973

    Related research 4

    1. Delayed Wound Healing in Keratin 6a Knockout Mice Molecular and Cellular Biology · 2000
    2. Keratin and Skin Disorders Cell biology international · 1996
    3. Keratin Expression in Basal Cell Carcinomas British Journal of Dermatology · 1992
    4. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989