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    Glossary Epidermis

    outermost skin layer providing protection against environmental factors

    The epidermis is the outermost layer of the skin, serving as a protective barrier against environmental factors such as pathogens, UV radiation, and physical injury. It is composed of multiple layers of cells, primarily keratinocytes, which undergo a continuous process of renewal and shedding. This layer also contains melanocytes, which produce melanin, the pigment responsible for skin color.

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    Research 10 of 1000+

    1. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000 · 1010 citations
    2. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009 · 503 citations
    3. Defining stem cell dynamics and migration during wound healing in mouse skin epidermis Nature Communications · 2017 · 363 citations
    4. Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis Development · 2009 · 338 citations
    5. Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours Development · 2004 · 335 citations
    6. Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas. The Journal of Cell Biology · 1982 · 277 citations
    7. The epidermis: rising to the surface Current opinion in genetics & development · 1994 · 238 citations
    8. Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis Proceedings of the National Academy of Sciences of the United States of America · 2012 · 221 citations
    9. Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter Journal of Investigative Dermatology · 2000 · 215 citations
    10. Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation. The Journal of Cell Biology · 1989 · 198 citations
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    1. Epidermal Growth Factor
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    Community 10

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