TLDR Trichilemmal keratinization is a unique process in hair follicles where the outer root sheath turns into keratin without a specific layer.
The study described trichilemmal keratinization as a distinct type of keratinization in the hair follicle, characterized by the conversion of the outer root sheath's stratified epithelium into anuclear keratin without a keratohyalin layer. This process was observed in the anagen phase below the sebaceous duct opening and in the catagen phase within the trichilemmal sac. The research, using electron microscopy on dog hairs, revealed complex infoldings of cells and unique ladder-like membrane coating granules in anagen, which were acid phosphatase-positive and potentially involved in the disintegration of the inner root sheath.
9 citations
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August 1980 in “Journal of Cutaneous Pathology” Rhodamin B stain is inconsistent for keratin in skin samples.
56 citations
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January 1970 in “Cell and Tissue Research”
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May 2021 in “Small ruminant research” The study found specific proteins that could mark different growth stages of cashmere goat hair and may help improve cashmere production.
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February 2004 in “British Journal of Dermatology” Keratin in mouse hair follicles is complex and plays specific roles.
86 citations
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May 2002 in “Journal of Investigative Dermatology” A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
121 citations
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December 2001 in “American Journal of Dermatopathology” TB and BCC tumors show similar follicular differentiation patterns.
79 citations
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December 1999 in “Mechanisms of Development” Whn is crucial for hair growth in certain areas by controlling a specific gene.
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January 1988 135 citations
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November 1987 in “Differentiation” Outer root sheath cells consistently express certain keratins influenced by their environment.
59 citations
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August 1981 in “PubMed” Trichilemmal keratinization is a unique process in hair follicles where the outer root sheath turns into keratin without a specific layer.
