Cytokeratins as Markers of Follicular Differentiation

    December 2001 in “ American Journal of Dermatopathology ”
    Hjalmar Kurzen, Lorenz Esposito, Lutz Langbein, Wolfgang Hartschuh
    Studysummary This study found that trichoblastomas and nodular basal cell carcinomas have similar cytokeratin expression patterns, indicating differentiation towards the outer root sheath epithelium.
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    Research cited in this study 14

    1. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    2. Immunolocalization of 5α-Reductase Isozymes in Acne Lesions and Normal Skin Archives of dermatology · 2000
    3. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999
    4. Basal Cell Carcinoma Possibly Originates From the Outer Root Sheath and/or the Bulge Region of the Vellus Hair Follicle Archives of Dermatological Research · 1999
    5. Cytokeratin 15 Expression in Trichoepitheliomas and a Subset of Basal Cell Carcinomas Suggests They Originate from Hair Follicle Stem Cells Journal of Cutaneous Pathology · 1999
    6. Keratin 15 Expression in Stratified Epithelia: Downregulation in Activated Keratinocytes Journal of Investigative Dermatology · 1999
    7. Cytokeratin Expression in Trichoblastic Fibroma, Trichoepithelioma, and Basal Cell Carcinoma British Journal of Dermatology · 1999
    8. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    9. Characterization of LHTric-1: A New Monospecific Monoclonal Antibody to Trichocyte Keratin Ha1 British Journal of Dermatology · 1997
    10. Immunohistochemical Demonstration of Keratin 19 Expression in Isolated Human Hair Follicles Journal of Investigative Dermatology · 1994
    11. Solid Basal Cell Epithelioma Possibly Originates From the Outer Root Sheath of the Hair Follicle PubMed · 1993
    12. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989
    13. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues II: Concomitant and Mutually Exclusive Synthesis of Trichocytic and Epithelial Cytokeratins in Diverse Human and Bovine Tissues (Hair Follicle, Nail Bed and Matrix, Lingual Papilla, Thymic Reticulum) Differentiation · 1988
    14. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues: Human and Bovine Hair Follicles Differentiation · 1988

    Related research 6

    1. TRPV3 Gain-of-Function Mutation Impairs Differentiation of Hair Follicle Inner Root Sheath ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2019
    2. Functional Analysis of Keratin Components in the Mouse Hair Follicle Inner Root Sheath British Journal of Dermatology · 2004
    3. Expression of E6 and E7 Papillomavirus Oncogenes in the Outer Root Sheath of Hair Follicles Extends the Growth Phase and Bypasses Resting at Telogen PubMed · 2000
    4. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    5. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987
    6. Outer Root Sheath Keratinization in Anagen and Catagen of the Mammalian Hair Follicle: A Seventh Distinct Type of Keratinization in the Hair Follicle - Trichilemmal Keratinization PubMed · 1981