Basal Cell Carcinoma Possibly Originates From the Outer Root Sheath and/or the Bulge Region of the Vellus Hair Follicle

    May 1999 in “ Archives of Dermatological Research ”
    Katharina Krüger, Ulrike Blume‐Peytavi, Constantin E. Orfanos
    Studysummary In this study, the immunohistochemical and lectin binding profiles of basal cell carcinoma closely resembled those of the outer root sheath of vellus hair follicles, suggesting a potential histochemical relationship.
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    Research cited in this study 13

    1. Immunohistochemical Demonstration of Keratin 19 Expression in Isolated Human Hair Follicles Journal of Investigative Dermatology · 1994
    2. Epithelial-Stromal Interactions in Basal Cell Cancer: The PDGF System Journal of Investigative Dermatology · 1994
    3. Cells Within the Bulge Region of Mouse Hair Follicle Transiently Proliferate During Early Anagen: Heterogeneity and Functional Differences of Various Hair Cycles Differentiation · 1994
    4. Solid Basal Cell Epithelioma Possibly Originates From the Outer Root Sheath of the Hair Follicle PubMed · 1993
    5. Hair Follicle Stem Cells: Their Location, Role in Hair Cycle, and Involvement in Skin Tumor Formation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    6. Lectin-Binding Profiles for Normal Skin Appendages and Their Tumors Journal of Cutaneous Pathology · 1992
    7. Keratin Expression in Basal Cell Carcinomas British Journal of Dermatology · 1992
    8. Expression of the L-Fucose Moiety on Infrainfundibular Follicular Keratinocytes of Terminal Follicles, Its Decreased Expression on Vellus and Indeterminate Follicles of Androgenetic Alopecia, and Re-Expression in Drug-Induced Hair Regrowth Journal of Investigative Dermatology · 1992
    9. Differentiation of Basal Cell Epithelioma-Like Changes Overlying Dermatofibroma Acta Dermato Venereologica · 1991
    10. Glycoconjugate Expression of Cells of Human Anagen Hair Follicles During Keratinization The Anatomical Record · 1990
    11. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues: Human and Bovine Hair Follicles Differentiation · 1988
    12. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987
    13. Differential Expression of Keratin 19 in Normal Human Epithelial Tissues Revealed by Monospecific Monoclonal Antibodies The Histochemical Journal · 1986

    Related research 5

    1. Keratins of the Human Hair Follicle International review of cytology · 2005
    2. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    3. Expression of E6 and E7 Papillomavirus Oncogenes in the Outer Root Sheath of Hair Follicles Extends the Growth Phase and Bypasses Resting at Telogen PubMed · 2000
    4. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    5. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987