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    Glossary Apoptosis

    natural process where cells intentionally die for organism health

    Apoptosis, also known as programmed cell death, is a natural process by which cells intentionally die to help maintain the health and balance of an organism. This process is crucial for development, immune function, and removing damaged or potentially harmful cells. In the context of hair, apoptosis can influence hair follicle cycling and contribute to conditions like alopecia if dysregulated.

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    1. Apoptosis in human skin development: Morphogenesis, periderm, and stem cells Developmental dynamics · 1994 · 253 citations
    2. Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis Archives of Toxicology · 2018 · 215 citations
    3. Apoptosis and keratin intermediate filaments Cell Death and Differentiation · 2002 · 180 citations
    4. Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes Journal of Investigative Dermatology · 2007 · 171 citations
    5. Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo andIn Vitro Journal of Investigative Dermatology · 1998 · 140 citations
    6. Roles of p38- and c-jun NH2-terminal kinase-mediated pathways in 2-methoxyestradiol-induced p53 induction and apoptosis Carcinogenesis · 2003 · 138 citations
    7. Do Hair Bulb Melanocytes Undergo Apotosis During Hair Follicle Regression (Catagen)? 1998 · 130 citations
    8. Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression American Journal of Pathology · 2006 · 128 citations
    9. <i>Sept4/</i> ARTS Regulates Stem Cell Apoptosis and Skin Regeneration Science · 2013 · 78 citations
    10. Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity Acta dermato-venereologica · 2017 · 66 citations
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    1. [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression Reddit · 4 Dec 2019
    2. Sugars ARE important for hair growth | Glycosaminoglycans as Hair Growth Stimulant Reddit · 30 Jul 2024
    3. Sunlight: Does it Stimulate Hair Growth or Hair Loss? Reddit · 9 Apr 2024
    4. HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia Reddit · 28 Oct 2023

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