Age-Induced Hair Greying: The Multiple Effects of Oxidative Stress

    August 2013 in “ International Journal of Cosmetic Science ”
    Miri Seiberg
    Studysummary This review discusses the role of oxidative stress in hair greying and suggests that understanding melanocyte susceptibility at different follicular locations may help develop therapies for preventing and reversing the process; it reports no new experimental results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 17

    1. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    2. Topical Application of Polygonum Multiflorum Extract Induces Hair Growth of Resting Hair Follicles Through Upregulating Shh and β-Catenin Expression in C57BL/6 Mice Journal of Ethnopharmacology · 2011
    3. Melanocyte Stem Cells: A Melanocyte Reservoir in Hair Follicles for Hair and Skin Pigmentation Pigment Cell & Melanoma Research · 2011
    4. Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells Cell stem cell · 2011
    5. Human Hair Follicle and Epidermal Melanocytes Exhibit Striking Differences in Their Aging Profile Involving Catalase ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    6. Senile Hair Graying: H2O2-Mediated Oxidative Stress Affects Human Hair Color by Blunting Methionine Sulfoxide Repair The FASEB Journal · 2009
    7. Aging of the Hair Follicle Pigmentation System International journal of trichology · 2009
    8. Oxidative Stress in Aging of Hair International Journal of Trichology · 2009
    9. Towards A Free Radical Theory Of Graying: Melanocyte Apoptosis In The Aging Human Hair Follicle As An Indicator Of Oxidative Stress Induced Tissue Damage ˜The œFASEB journal · 2006
    10. Changes in Different Melanocyte Populations During Hair Follicle Involution (Catagen) ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    11. Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model Photochemistry and Photobiology · 2004
    12. Hair Cycle and Hair Pigmentation: Dynamic Interactions and Changes Associated with Aging Micron · 2003
    13. Hair Darkening in Porphyria Cutanea Tarda British journal of dermatology/British journal of dermatology, Supplement · 2002
    14. Melanocyte Subpopulation Turnover During the Human Hair Cycle: An Immunohistochemical Study Pigment cell research · 2000
    15. Do Hair Bulb Melanocytes Undergo Apoptosis During Hair Follicle Regression (Catagen)? ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    16. Expression of the Bcl-2 Proto-Oncogene in the Cycling Adult Mouse Hair Follicle Journal of Investigative Dermatology · 1994
    17. The Hair Cycle of the Mouse and Its Importance in the Study of Sequences of Experimental Carcinogenesis Annals of the New York Academy of Sciences · 1951

    Related research 2

    1. Melanocyte Stem Cells: A Melanocyte Reservoir in Hair Follicles for Hair and Skin Pigmentation Pigment Cell & Melanoma Research · 2011
    2. Functionally Distinct Melanocyte Populations Revealed by Reconstitution of Hair Follicles in Mice Pigment Cell & Melanoma Research · 2010