Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model

    November 2004 in “ Photochemistry and Photobiology ”
    I Emerit, Paulo Filipe, João Freitas, Jany Vassy
    TLDR Superoxide dismutase (SOD) can prevent hair graying in mice.
    The study investigated the protective effect of superoxide dismutase (SOD) against hair graying in a mouse model. Mice with black hair were treated on one side with a SOD-containing gel and exposed to psoralen plus UV-A, while the other side received a gel without SOD. In 27 out of 30 mice, the SOD-treated side regrew black hair, whereas the untreated side regrew gray or white hair. The study demonstrated that SOD penetrated the skin and protected melanocyte DNA from damage by dismutating superoxide radicals, suggesting that photosensitization reactions contribute to hair graying and can be mitigated by antioxidants like SOD. This mechanism warrants further investigation in human hair graying.
    Discuss this study in the Community →

    Related Community Posts Join

    4 / 4 results

      community Which mesotherapy should I choose?

      in Research/Science  1 upvotes 6 months ago
      A user is considering adding PRP and mesotherapy to their hair loss treatment and is deciding between two options: Promoitalia, which contains Phosphatidic acid, Riboflavin, and Superoxide dismutase, and the more expensive Melsmon, a human placenta derivative. They seek advice on which option to choose based on effectiveness and scientific backing.

      community Anything you use without scientific backing, just trusting your gut?

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

    Similar Research

    5 / 811 results