Aging and Anti-Aging in Hair and Hair Loss

    January 2014 in “ Elsevier eBooks
    Chia-Han Yang, Chih Chiang Chen, Wen Chieh Chen
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    TLDR Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
    The document from 2014 examines the aging process in hair follicles, the decrease in hair density and growth rate with age, and the graying of hair due to the loss of melanocyte stem cells. It highlights the role of chronic inflammation, or "inflammaging," in hair loss and diseases like alopecia areata (AA) and androgenetic alopecia (AGA), and the impact of stress on conditions like telogen effluvium. The document also discusses scarring alopecia, anti-aging strategies involving antioxidants and anti-inflammatory agents, and the potential of hormone replacement therapy and phytoestrogens. It emphasizes the importance of oxidative stress in hair follicle aging and the beneficial effects of polyphenols, vitamins, and nutraceuticals on hair health. However, the document does not provide specific study designs or participant numbers, so the strength of the evidence is unclear.
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