Obesity and Low-Grade Inflammation Among Young Finnish Men With Early-Onset Alopecia

    January 2007 in “ Dermatology
    Päivi Hirsso, Ulla Rajala, Liisa Hiltunen, Jari Jokelainen, Sirkka Keinänen‐Kiukaanniemi, Simo Näyhä
    TLDR Young Finnish men with more severe hair loss may have higher inflammation and obesity, increasing future heart disease risk.
    The study investigated the association between early-onset alopecia and low-grade inflammation in young Finnish men, using high-sensitivity C-reactive protein (hs-CRP) as a marker. The study included 727 men aged 25-34 years. Results indicated that men with moderate to extensive alopecia had higher body mass index and larger body measurements compared to those with little to no alopecia. Although differences in waist-to-hip ratio, diastolic blood pressure, and hs-CRP were not statistically significant, an increase in hs-CRP was associated with an increase in waist-to-hip ratio among men with more severe alopecia. The findings suggested a link between moderate to extensive alopecia and low-grade inflammation, which is a predictor of future cardiovascular disease, particularly when combined with central obesity in men under 35 years.
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