Clinical Profile of Androgenic Alopecia and Its Association with Cardiovascular Risk Factors

January 2019 in “ Indian Journal of Dermatology ”

Rita V Vora, Rahul Krishna S Kota, Rochit R Singhal, Gopikrishnan Anjaneyan

androgenic alopecia AGA metabolic syndrome MetS abdominal obesity hypertension high-density lipoprotein male pattern baldness HDL

Studysummary This study found that men with early-onset androgenic alopecia had a higher prevalence of cardiovascular risk factors, indicating that early screening for metabolic syndrome may be beneficial in this population.

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The study investigated the clinical profile of androgenic alopecia (AGA) and its association with cardiovascular risk factors in men aged 25-40 years, involving 50 men with early-onset AGA and 50 controls. Results showed that metabolic syndrome (MetS) was present in 10% of AGA cases compared to 2% of controls, though not statistically significant. However, AGA patients had significantly higher rates of abdominal obesity, hypertension, and lowered high-density lipoprotein levels. The study concluded that men with early-onset AGA had a higher prevalence of cardiovascular risk factors, suggesting that early screening for MetS and its components could be beneficial for these patients.

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research Metabolic Syndrome in Androgenic Alopecia

16 citations , January 2016 in “Indian Journal of Dermatology, Venereology and Leprology”

This study found that men with early-onset androgenic alopecia had a higher prevalence of metabolic syndrome compared to controls without the condition.

research Is Early Onset Androgenic Alopecia a Marker of Metabolic Syndrome and Carotid Artery Atherosclerosis in Young Indian Male Patients?

24 citations , January 2015 in “International Journal of Trichology”

This research observed that among young men with androgenic alopecia, there was a significant association with metabolic syndrome compared to healthy controls, suggesting AGA as a potential early marker for metabolic risk.

research Association of Premature Androgenetic Alopecia and Metabolic Syndrome in a Young Indian Population

16 citations , January 2014 in “International Journal of Trichology”

This study found that male Indian patients under 30 with early androgenetic alopecia were more likely to have metabolic syndrome compared to age-matched controls.

research Androgenetic Alopecia and Risk of Coronary Artery Disease

24 citations , January 2013 in “Indian Dermatology Online Journal”

This study found that males with androgenetic alopecia had a higher risk of coronary artery disease, with significant differences in several lipid and blood pressure markers compared to controls.

research Androgenetic Alopecia and Cardiovascular Risk Factors in Men and Women: A Comparative Study

110 citations , July 2010 in “Journal of The American Academy of Dermatology”

Hair loss linked to higher heart disease risk in both men and women.

research A Comparative Study of Dyslipidemia in Men and Women with Androgenic Alopecia

37 citations , January 2010 in “Acta dermato-venereologica”

This study found that both men and women with androgenic alopecia had significantly higher triglycerides, total cholesterol, and LDL-C and lower HDL-C levels than controls, suggesting increased dyslipidemia prevalence.

research Hypertension and Aldosterone Levels in Women with Early-Onset Androgenetic Alopecia

45 citations , November 2009 in “British Journal of Dermatology”

This study found that women with early-onset androgenetic alopecia had higher aldosterone levels and blood pressure, suggesting a possible link to the increased prevalence of hypertension in this group.

research Evaluation of Lipid Levels in Androgenetic Alopecia Compared with Control Group

27 citations , March 2008 in “Journal of The European Academy of Dermatology and Venereology”

Men with a certain type of hair loss (AGA) have higher bad cholesterol and lower good cholesterol levels, making them more likely to get heart disease.

research Association of Androgenetic Alopecia and Hypertension

34 citations , August 2007 in “PubMed”

This study found a strong association between androgenetic alopecia and hypertension in Caucasian men, independent of age.

research Obesity and Low-Grade Inflammation Among Young Finnish Men With Early-Onset Alopecia

72 citations , January 2007 in “Dermatology”

This study found a correlation between moderate to extensive alopecia and low-grade inflammation, a cardiovascular risk marker, particularly in young men under 35 with central obesity.

research Early Onset of Androgenetic Alopecia Associated With Early Severe Coronary Heart Disease: A Population-Based, Case-Control Study

56 citations , June 2001 in “European journal of cardiovascular prevention & rehabilitation”

This study found that men with early-onset androgenic alopecia have a higher risk of needing coronary revascularization before age 60 compared to those with later onset or no hair loss.

research Androgenetic Alopecia in Men and Women

77 citations , March 2001 in “Clinics in Dermatology”

This article discusses treatment approaches for female pattern hair loss and concludes that available medical treatments are effective in reversing or stabilizing the condition in most cases of mild-to-moderate severity.

research Early Androgenetic Alopecia as a Marker of Insulin Resistance

115 citations , September 2000 in “The Lancet”

Early hair loss may indicate risk of insulin resistance.