Androgenetic Alopecia and Insulin Resistance in Young Men

October 2009 in “ Clinical Endocrinology ”

José Gerardo González-González, Leonardo Mancillas-Adame, Mercedes Fernández-Reyes, Minerva Gómez-Flores, Fernando J. Lavalle-González, Jorge Ocampo-Candiani, Jesús Zacarías Villarreal-Pérez

androgenetic alopecia insulin resistance metabolic syndrome Hamilton-Norwood classification AGA

TLDR Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.

This study from 2009 investigated the relationship between androgenetic alopecia (AGA) and insulin resistance in young men. The study found that young male AGA cases had a higher prevalence of insulin resistance and metabolic syndrome than controls. The study recommends assessing insulin resistance and cardiovascular-related features and disorders in all young males with stage III or higher AGA, according to the Hamilton-Norwood classification. The study suggests that AGA may be a marker for insulin resistance and that young men with AGA should be screened for metabolic disorders.

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

15 / 15 results

research Association of Androgenetic Alopecia With Smoking and Its Prevalence Among Asian Men

91 citations, November 2007 in “Archives of Dermatology”

Smoking linked to hair loss in Asian men.

research Androgenetic Alopecia: Clinical Features, Classification, and Treatments

103 citations, June 2007 in “Endocrinology and Metabolism Clinics of North America”

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

research Sexual Hormones in Human Skin

305 citations, February 2007 in “Hormone and metabolic research”

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

research The Hair Follicle as an Estrogen Target and Source

159 citations, July 2006 in “Endocrine Reviews”

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Health-Related Quality of Life and Physical Well-Being Among a 63-Year-Old Cohort of Women With Androgenetic Alopecia: A Finnish Population-Based Study

research Health-Related Quality of Life and Physical Well-Being Among a 63-Year-Old Cohort of Women With Androgenetic Alopecia: A Finnish Population-Based Study

24 citations, August 2005 in “Health and Quality of Life Outcomes”

Women with androgenetic alopecia experience worse physical well-being and quality of life, but similar mental health compared to those without it.

research The Natural History of Androgenetic Alopecia

12 citations, January 2005 in “Journal of Cosmetic Dermatology”

AGA affects many, progresses differently, and early treatment is crucial.

research Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia

33 citations, October 2004 in “Archives of Dermatological Research”

Large prostate links to more hair loss, but age of onset doesn't affect it.

research Pathogenesis of Androgenetic Alopecia

52 citations, April 2004 in “Journal of The American Academy of Dermatology”

Male pattern baldness involves three mechanisms and finasteride can help reverse it.

research Family History and Risk of Hair Loss

49 citations, January 2004 in “Dermatology”

Men with a family history of hair loss are more likely to experience it themselves, especially if both parents have hair loss.

research Androgenetic Alopecia in Men Aged 40-69 Years: Prevalence and Risk Factors

155 citations, December 2003 in “British Journal of Dermatology”

Hair loss increases with age; alcohol raises risk, more female partners lowers it.

research Early Onset of Androgenetic Alopecia Associated With Early Severe Coronary Heart Disease: A Population-Based, Case-Control Study

56 citations, June 2001 in “European journal of cardiovascular prevention & rehabilitation”

Early balding linked to higher heart disease risk.

research Early Androgenetic Alopecia as a Marker of Insulin Resistance

115 citations, September 2000 in “The Lancet”

Early hair loss may indicate risk of insulin resistance.

research Intracrinology and the Skin

82 citations, January 2000 in “Hormone Research in Paediatrics”

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

research The Biology of Hair Follicles

1113 citations, August 1999 in “The New England Journal of Medicine”

Hair follicle biology advancements may lead to better hair growth disorder treatments.

research The Risk of Coronary Heart Disease in Men with Androgenetic Alopecia

34 citations, March 1999 in “Journal of The European Academy of Dermatology and Venereology”

Bald men may have higher heart disease risk.

Related Community Posts Join

6 / 1000+ results

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Do we have to be junkies? That's funny

in Research/Science 13 upvotes 5 months ago

The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 2 months ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community Why balding gets worse in every generation?

in Chat 81 upvotes 5 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community Are a lot of men already losing their hair at 25?

in Chat 153 upvotes 1 year ago

The conversation discusses the perception of increased hair loss among young men, with some attributing it to heightened awareness or environmental factors. Various treatments are mentioned, including Minoxidil, Finasteride, microneedling, scalp massages, and future hair transplant methods.

community In my opinion baldness is more prevalent now and it's being ignored..

in Chat 236 upvotes 1 year ago

The conversation is about the prevalence of baldness among young men and the potential factors contributing to it. Specific treatments mentioned include minoxidil and finasteride.

Similar Research

5 / 1000+ results

research Is There Really a Relationship Between Androgenetic Alopecia and Metabolic Syndrome?

15 citations, November 2015 in “Dermatology Research and Practice”

No clear link between hair loss and metabolic syndrome, but some differences in blood pressure and glucose levels.

research Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study

34 citations, July 2014 in “Indian Dermatology Online Journal”

Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.

research The Association of Metabolic Syndrome and Insulin Resistance in Early-Onset Androgenetic Alopecia in Males: A Case-Control Study

10 citations, January 2019 in “Indian Journal of Dermatology”

Early-onset male hair loss is linked to metabolic syndrome, suggesting a need for heart health monitoring and lifestyle changes.

research Factors Associated With Early-Onset Androgenetic Alopecia: A Scoping Review

March 2024 in “PLOS ONE”

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

research Is Early Onset Androgenic Alopecia a Marker of Metabolic Syndrome and Carotid Artery Atherosclerosis in Young Indian Male Patients?

24 citations, January 2015 in “International Journal of Trichology”

Early balding in young Indian men may indicate a higher risk of metabolic syndrome and potential heart disease.