The Association of Metabolic Syndrome and Insulin Resistance in Early-Onset Androgenetic Alopecia in Males: A Case-Control Study

    January 2019 in “ Indian Journal of Dermatology ”
    Mukunda Ranga Swaroop, B. V. K. Vijaya Kumar, BD Sathyanarayana, Yogesh D, Jigalikoppa Raghavendra, Priyanka Kumari
    TLDR Early-onset male hair loss is linked to metabolic syndrome, suggesting a need for heart health monitoring and lifestyle changes.
    The study examined the link between metabolic syndrome (MS) and insulin resistance (IR) in males with early-onset androgenetic alopecia (AGA), involving 50 male patients with AGA and 50 age-matched controls. It found that 30% of the AGA group had MS, a significant difference compared to 8% in the control group (P = 0.005), but there was no significant association between AGA and IR (P = 0.23). The findings indicated that early-onset AGA in males was linked to MS, suggesting the importance of monitoring for cardiovascular disorders and implementing lifestyle changes to reduce coronary heart disease risk.
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